Using Drugs to Ensure IUI Success - Clomid

In order to optimize the procedure, often ovulation-inducing drugs are prescribed in order to stimulate the ovaries to produce more eggs. The availability of more eggs increases the chances of conception. The most commonly prescribed drug for ovarian stimulation is clomiphene citrate, known as Clomid.

Clomid's side effects

The side effects of Clomid are moodiness, depression, nausea and headaches. Occasionally women may experience hot flashes or vision problems. In some cases, overstimulation of the ovaries can occur which leads to pelvic pain and unchecked can lead to ovarian cysts.

Some studies have indicated that ovulation-inducing drugs can cause the endometrium (lining of the uterus) to thin out and it can also create changes in the cervical mucus. These two facts can be a hindrance to conception. However, overall the impact of side-effects from Clomid tends to be mild and disappear when the medication is stopped.

Using Injectables for IUI Success

If Clomid doesn't work, then injectable medications for IUI will be used. These injectables mimic either follicle stimulating hormone (FSH) or luteinizing hormone (LH) or, in some cases, both. These hormones are called gonadotropins and their function is to stimulate the release of eggs at the right time.

Side effects of gonadotropins

Gonadotropins are known for causing mood swings and depression and it is possible to have some swelling and rash around the injection site. Breast tenderness, abdominal pain and bloating are also common side-effects of using injectable hormones to facilitate IUI. Any ovulation stimulating drug can cause overstimulation of the ovaries so the administration must be carefully governed.

Sperm Quality for IUI Success

Equally important is the health of the sperm being used in IUI. One of the reasons IUI has a reasonable success rate is attributable to the preparation of the sperm. Washing the sperm before insemination removes toxins from the semen and sperm and isolates the healthiest, strongest sperm for insemination.

Some doctors like to perform two inseminations in one cycle in order to increase the chance of a successful IUI. Learn more about sperm preparation and washing in this section of our site.

Table of Contents
1. IUI Success
2. How to make more eggs
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